J. Craig Venter, genome scientist, dies at 79

Summary

Genome scientist J. Craig Venter, who helped lead the race to decode human DNA, died Wednesday in San Diego at 79.

Why this matters

Venter played a central role in genomics, including the competition to sequence the human genome, which reshaped biomedical research. His work also advanced methods used to decode bacterial and animal genomes.

J. Craig Venter, a scientist and entrepreneur who helped lead the race to decode the human genome, died Wednesday in San Diego. He was 79.

His death was announced by the J. Craig Venter Institute, a nonprofit research organization he founded in San Diego and Rockville, Maryland. The institute said Venter had been hospitalized recently because of side effects from cancer treatment.

In the 1990s, Venter entered the competition to decode the human genome, arguing that the Human Genome Project, a $3 billion government effort, was moving slowly and that a faster method could succeed.

In 2000, Venter’s company, Celera, joined a rival group in announcing that they had assembled the first human genomes, a major step in research into the genetic basis of disease and human origins.

In 1995, Venter and colleagues published the first decoded bacterial genome, for Haemophilus influenzae, along with annotations of the organism’s genes. The work gave researchers a full view of the genetic components of a free-living organism and helped spur efforts to sequence the genomes of pathogens.

His team later sequenced the fruit fly genome to test whether its whole-genome shotgun sequencing approach could be applied to the human genome. The fruit fly genome was decoded in 2000.

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